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Glyconutrients / Glyconutritionals
http://www.avalonhealthinfo.com/articles/463/1/Glyconutrients--Glyconutritionals/Page1.html
By Denice Moffat, Dr.
Published on 08/3/2007
 
Glyconutrients are not vitamins, minerals, herbals, homeopathics or enzymes. They are a class all to themselves. They are supplements derived from nature that have been formulated based on a new understanding in biochemistry of how our bodies maintain health at the cellular level. This new discovery is as significant as the discovery of the role of vitamins, essential fatty acids, and amino acids in how the body functions. Glyconutritionals are the foods and nutritional supplements that provide saccharides along with other glycoforms (lipids and proteins) essential to the body, but which are scarce in most diets.

It's Role in People & Animals' Health and Wellness
Glyconutrients are not vitamins, minerals, herbals, homeopathics or enzymes. They are a class all to themselves. They are supplements derived from nature that have been formulated based on a new understanding in biochemistry of how our bodies maintain health at the cellular level. This new discovery is as significant as the discovery of the role of vitamins, essential fatty acids, and amino acids in how the body functions. Glyconutritionals are the foods and nutritional supplements that provide saccharides along with other glycoforms (lipids and proteins) essential to the body, but which are scarce in most diets. Over 20,000 studies have been conducted on individual glyconutrients, and virtually all of them have positive outcomes and show great promise as healers of the future. Based on the knowledge that the body can heal itself through cell to cell communication if given the proper nutrients, glyconutrients are seen by many scientists and doctors as the missing link to optimal health.

Why are we experiencing mounting health challenges? According to the 1992 Earth Summit, the USA has the worst soil in the world - 85% depleted. This means the potency of our food supply is not able to sustain optimum health. The amount of toxins in our environment has reached a level where the FDA now has designated "permissible" levels of dioxin and other harmful chemicals in the environment. Today we have over 300 chemical toxins including dioxin in the tissues that were not found in any human before 1940.1 These toxins have been shown to bind to receptors, blocking important enzymatic reactions in the body. One of the harmful effects of toxins such as DDT and dioxins is that they mimic hormones in the body causing disruption and confusion in the endocrine system.

Processed food and fast foods are depriving us of even more essential nutrients. Many scientists believe that commercial farming, which burns out nutrients and adds poisons to the soil, as well as shipping foods "green" to ripen upon trucks, are major contributors to ill health. Many corporations continue activities harmful to our health to increase profits at the cost of our ecosystem and food chain. They do not inform the public about the true extent of the problem created by toxic substances and harmful additives in our foods nor about the environmental pollution generated from their manufacturing plants. A movie released a few years ago, A Civil Action, depicts this lack of accountability in the corporate arena. Finally, according to research scientist named Andreas Hartman "A class of broad spectrumantibiotics in drinking water is causing toxicity to human DNA!" Given these harsh challenges, one might seriously ask how can we best protect ourselves and optimize our health?

Dr. Omelchuk believes that there is a direct relationship between the regeneration of his brain cells and the glyconutritionals that he used. "Medical researchers told me after my stroke that I had lost thirty percent of my brain capacity," he said. "I had myself tested after I had been talking the supplements and was told that all of my mental faculties were normal. My verbal capacity is in the 97th percentile. I have my life back! Glyconutritionals are responsible for my recovery and for the quality of life that I am able to share with my wife today." Neither his medical training nor his medical teaching or practice was complemented with education in nutrition, Dr. Omelchuk said. "Some members of the medical community are admitting on a daily basis that our food chain is depleted and that the only way that we are going to get the essential nutrients that our bodies need is through supplementation," he said. "Glyconutritionals could be one of the greatest nutritional discoveries of the 20th century," he said. "Unfortunately, physicians and many others in the field of health care know very little or nothing about them, even though there is abundant peer-reviewed scientific validation as to their efficacy in supporting the body's normal functions of recovery from chronic diseased

conditions."

The book Sugars That Heal—The New Healing Science of Glyconutrients, written by Emil Mondoa, M.D., published in late 2001 and available through major booksellers, is an indication that this scientific discovery is reaching the mainstream public reading audience. One book reviewer wrote a synopsis of the book describing how these glyconutrients help us maintain health: “Even tiny amounts of these sugars--or lack of them--have profound effects. In test after test conducted at leading institutes around the world, saccharides have been shown to lower cholesterol, increase lean muscle mass, decrease body fat, accelerate wound healing, ease allergy symptoms, and allay autoimmune diseases such as arthritis, psoriasis, and diabetes. Bacterial infections, including the recurrent ear infections that plague toddlers, often respond remarkably to saccharides, as do many viruses--from the common cold to the flu, from herpes to HIV. The debilitating symptoms of chronic fatigue syndrome, fibromyalgia, and Gulf War syndrome frequently abate after adding saccharides. And, for cancer patients, saccharides mitigate the toxic effects of radiation and chemotherapy--while augmenting their cancer-killing effects, resulting in prolonged survival and improved quality of life.”

Dr. Omelchuk suffered a massive cerebellar aneurysm in 1987 that nearly cost him his life. He had a 10-hour surgery, was in a coma, and underwent extensive rehabilitation. Initially he could not talk or walk; he was a total invalid. He had been on home therapy, reaching a plateau after 7 years. Even then, he could only lecture 3 hours and had major limitations. His short-term memory was gone. In April 2000, he was introduced to the newly discovered field of glyconutrients and the research behind them. Within a couple of months he regained his memory, his stamina, his ability to sleep well, and his self-esteem.

Dr. Benjamin Solomon Carson Sr - "Glyconutritionals could be one of the greatest nutritional discoveries of the 20th century. Unfortunately, physicians and many others in the field of health care know very little or nothing about them, even though there is abundant peer-reviewed scientific validation as to their efficacy in supporting the body's normal functions of recovery from chronic diseased conditions." Dr. Benjamin Solomon Carson Sr. is the director of pediatric neurosurgery at Johns Hopkins University in Baltimore. He cured his prostate cancer with glyconutrients.

Gunter Blobel, M.D., Ph.D. - "Glyconutrients are a new and more specialized type of nutraceutical. They support the process our individual tissue cells use to recognize, and communicate with, each other. The work that Dr. Blobel and many others have done let us understand the importance of good cell communication to ensure good health. The discovery of Glyconutrients and their role in human health is now in Mainstream Medicine."


The Key to Healthy Cells and Healthy Bodies
An increasing number of research scientists and doctors believe that eight specific carbohydrates (saccharides), represent the key to cellular communication as these sugars combine with proteins to create the glycoprotein chemical messengers. Only two of the eight are commonly found in our typical modern diets: glucose and galactose. The other sugars are Mannose, Fucose, Xylose, N-Acetylglucosamine, N-Acetylgalactosamine, and N-Acetylneuraminic acid. The body has the potential to convert glucose and galactose to the other six through enzyme exchanges. However, the conversion process requires considerable energy, and is susceptible to interference from certain disease processes, various medications and free radicals. Oxidative damage from free radicals can also cause destruction of existing glycoprotein structures, making it necessary to convert some sugars into others to repair the damage. Living in our current environment, our bodies simply cannot keep up with this conversion/repair process. Further validation of the essential nature of these carbohydrates can be found in an article about the immune-enhancing benefits of breastfeeding.6 Five of the eight carbohydrates thought to be essential for cell-to-cell communication are ingredients in human breast milk and also in the glyconutrient formula Ambroto.e.

Healthy bodies, comprised of many components working together in sophisticated harmony, must have accurate biochemical communication to function correctly. In its most basic form, this communication occurs at the cellular level and is referred to by molecular biologists as cell-to-cell communication. When you look at any body function, it is clear they all require cellular communication. A major breakthrough has occurred recently with the discovery of how our cells communicate; that cells have a language, made up of "letters" and "words." The "words" are called glycoproteins made up of various sugar molecules known as saccharides attached in pearl-like strands to protein stems. Some of the connections for the saccharides are to lipids forming glycolipids. These "words" extend off the surface of every cell and can change thousands of times in a second. Cells actually touch each other to communicate reading each other with cell surface messages. Disease and dysfunction occurs when the components necessary for cell-to-cell communication are absent.4 As John Hodgson wrote in an article called "Capitalizing on Carbohydrates", "Almost without exception, whenever two or more living cells interact in a specific way, cell surface carbohydrates will be involved. From the first meeting of sperm and egg, through embryo genesis, development and growth, carbohydrate molecules confer exquisite specificity upon cell-cell interactions."

Disease is a symptom of one or more body systems in distress. When you nourish and balance the systems, you give your body what it requires to resist, repair and overcome disease, and to achieve optimal health.Research over the past decade has demonstrated the importance of essential fatty acids and essential proteins (amino acids). Now scientists and nutritionists are just beginning to understand that there are essential sugars as well. Eight essential sugar compounds function individually as building blocks to assemble a nearly infinite variety of complex molecules known as glycans or sugar chains. Glyconutrients research field has been in numerous peer reviewed articles and text such as Harper's Biochemistry, Acta-Anotomica (has the latest high tech grad level research in cellular biology - published in Europe), Science Magazine, Positive Health" Magazine, and more. Are We Deficient Deficient In Essential Key Nutrients?



Miracle Sugars: The Glyconutrient Link to Disease Prevention and Improved Health

The sugars found on all glyconutrients also address the workings of the brain and nervous system – from memory and sleep to anxiety and depression. In addition, they have a role in helping the body handle cholesterol and fats by lowering triglycerides and low-density lipoproteins (LDL) while, at the same time, raising the good cholesterol (HDL). Commercials have long touted the benefits of eating oatmeal to bring down cholesterol. What is not mentioned is that it is the sugars (beta-glucans) in oatmeal that are responsible.

Another important essential sugar function is to help retain bone density and muscle mass. The body undergoes wear and tear as it ages. Cells and tissues need to be replaced, remodeled, and renewed continually. Exercise helps the body to develop new blood vessels while increasing muscle mass. Certain kinds of tissues adapt to exercise by increasing the size and number of cells. Adaptation, healing, and recovery are all forms of tissue remodeling. Essential sugars play important roles in these processes.

There is so much potential to these sugars that it is mind-boggling. What is included here is only just the beginning of what is to come. The excitement that must have reverberated when penicillin was developed is nothing compared to the excitement as science continues to find out all the capabilities of this maligned substance. This is not a gimmick or a fad but the actual foundation upon which other nutrients can build. We will all have to stay tuned. Glyconutrients

Without the proper nutrients, our organs and body systems begin a slow process of degeneration. Degenerative diseases are the leading cause of death in this country, and are growing dramatically. Cancer, diabetes, heart disease, arthritis -- these are degenerative processes that cause immeasurable human suffering. In addition, emotional stress in the 20th Century is at an all time high and directly impacts our well-being.

Glycobiology has now established that every cell in the mammalian body requires eight necessary sugar molecules in order to function effectively. These sugars combine with protein and fat molecules into glycoforms that attach themselves to the surfaces of every cell in the body. Under an electron microscope, they look like weird trees growing on the cell surface. One of their most important functions there is to allow cells to communicate effectively with each other. To the degree that these "super sugars" are deficient, cell-to-cell communication tends to break down and some form of illness starts to develop.

Michael D. Schlachter, MD speaks out to physicians worldwide emphasizing why doctors must integrate glyconutrient technology into their medical practice. - "After seeing the benefits and noting the scientific validation of these nutrients, I no longer consider the addition of proper nutrients to the diet as a luxury. It is a fundamental and integral part of helping my patients achieve and maintain the health that they want and deserve. The biggest revolutionary change in the war against disease is represented by glyconutrients. If you do not want to become a patient (and therefore a statistic) you need to answer in your own mind and heart if what you are doing for your health is optimal, and if not what else can you do." Michael D. Schlachter, MD, is on the Board Certified Internal Medicine and Pulmonary Disease, Clinical Instructor at the University of Nevada Medical School.

Susan Lord, MD - "Glyconutrients came to my attention, actually, about two years ago, when I was working with a patient with hepatitis-C. I had pulled out all of the stops with her, and I was getting nowhere, and her health condition was deteriorating before my eyes, to the point that she was nearly bedridden. Working on the Internet, she came across these products called glyconutrients and started taking them. She stopped everything that I gave her and started nothing but these, and her health started improving immediately, to the point where she is in excellent health today. That got my attention. Last year for our cancer conferences, I did more research on these supplements. I understood that they seemed to be helping cancer patients who had gone through chemo and radiation. It helped them with quality of life and keeping their blood counts up. Last year at the cancer conference, we invited Dr. Glen Holland (?), who is an oncologist from the Midwest, to come and to give a very, very preliminary presentation about these compounds. It was a little more than anecdotal. He did have some data, but it was very preliminary. But it looked promising

Martin Milner, N.D., - "We are finding glyconutrient deficiencies associated with a large range of diseases."

Dr John Axford - "Sugars are going to be the molecules of the future. Glycobiology is one of the last frontiers of science to be conquered and is going to be at the cutting edge of a large number of discoveries and therapies over the next decade." Dr Axford is immediate past-President of the Royal Society of Medicine, Section of Clinical Immunology & Allergy

Dr. John Rollins - "Glyconutrients are one of the most important healthcare discoveries of the 21st century." Dr. Rollins is the former Assistant Professor of Microbiology at Howard University’s School of Medicine

Dr. M. Schlachter, MD - "The Biggest revolutionary change in the war against disease is represented by Glyconutrients"



Are We Deficient Deficient In Essential Key Nutrients?
Scientists have recently discovered that our modern diet is missing some very vital nutrients, and surprisingly enough, these missing nutrients are essential fatty acids (ie: omega 3 fatty acids as in flaxseed oil and fish oil) and essential sugars. The Greek word "Glyco" means "Sugar". Most people think of sugar as being bad for you. However, there are actually TWO kinds of sugars. One is the refined or "extracellular" sugars which have been long associated with human disease. The other sugars are "intracellular" which can be found in fruits and vegetables and provide the body with nutrition it needs. There are over 20,000 studies conducted annually on glycoforms alone. Researchers from universities and major pharmaceutical companies realize the importance of this new discovery. Putting the terms "sugar" and "health" together seems almost like a paradox, but emerging evidence shows that certain types of sugars - commonly called saccharides or glyconutrients - are responsible for fighting off disease and maintaining overall health.

We've all been bombarded with warnings about the evils of consuming too much sugar. But, in fact, for our bodies to function properly, we need small amounts of eight essential sugars, only two of which--glucose and galactose--are commonly found in our limited, overprocessed diets. When all eight sugars are available, the health benefits can be breathtaking: Individuals regain their ability to fight disease, reactivate their immune systems, and are able to ward off infection. Based on cutting-edge research in the rapidly evolving science of glyconutrients, Sugars That Heal is an exciting new approach to health and disease prevention.

If you eat a diet rich in unprocessed fruits and vegetables, you're supplying your body with many glyconutrients. But just because they're sugars doesn't mean they taste sweet. For instance: Fucose, xylose and mannose are three of the eight essential sugar compounds. Mushrooms and seeds contain fucose; rye, barley and yeast contain xylose; and mannose can be found in broccoli, cabbage and seeds.

As medical doctor and scientific researcher Emil Mondoa explains, these eight essential sugars, known as saccharides, are the basis of multicellular intelligence--the ability of cells to communicate, cohere, and work together to keep us healthy and balanced. Even tiny amounts of these sugars--or lack of them--have profound effects. In test after test conducted at leading institutes around the world, saccharides have been shown to lower cholesterol, increase lean muscle mass, decrease body fat, accelerate wound healing, ease allergy symptoms, and allay autoimmune diseases such as arthritis, psoriasis, and diabetes. Bacterial infections, including the recurrent ear infections that plague toddlers, often respond remarkably to saccharides, as do many viruses--from the common cold to the flu, from herpes to HIV. The debilitating symptoms of chronic fatigue syndrome, fibromyalgia, and Gulf War syndrome frequently abate after adding saccharides. And, for cancer patients, saccharides mitigate the toxic effects of radiation and chemotherapy--while augmenting their cancer-killing effects, resulting in prolonged survival and improved quality of life.

Disease is a symptom of one or more body systems in distress. When you nourish and balance the systems, you give your body what it requires to resist, repair and overcome disease, and to achieve optimal health. While challenges to our health (virus, parasites, bacteria, toxins) are at an all-time high, our nutritional intake to protect ourselves from these challenges is at its lowest level ever. Glycoproteins are used by the body for many other purposes including building enzymes, hormones, immunoglobulins and antibodies. Glycoproteins are found inside every cell. Glycolipids help build the brain and nervous system. Fucose and mannose can provide significant cancer tumor suppression. The sugars are important for a strong immune system, and this also helps fight cancer.

Glyconutrients have powerful effects on the immune system. When used along with surgery, chemotherapy, and/or radiation, glyconutrients have proven to help lessen the side effects of these treatments while helping the body to recover and heal itself more quickly than if only the treatments were implemented.